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See how you may be able to save on Jaypirca and get support along the way

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Jaypirca Savings Card

Eligible, commercially insured patients pay as little as $0 a month.*

Governmental beneficiaries excluded, terms and conditions apply.

Paying for treatment shouldn't be an additional concern for you and your loved ones, so we've created the Jaypirca Savings Card, which may help you manage treatment costs.

Need a savings card?

*Subject to Lilly USA, LLC's (Lilly's) right to terminate, rescind, revoke or amend the Jaypirca Savings Card Program (“Card”) eligibility criteria and/or Card terms and conditions which may occur at Lilly's sole discretion, without notice, and for any reason, the Card expires and savings end on 12/31/2024. Card savings are not available to patients without commercial drug insurance or who are enrolled in any state, federal, or government funded healthcare program, including, without limitation, Medicaid, Medicare, Medicare Part D, Medicare Advantage, Medigap, DoD, VA, TRICARE®/CHAMPUS, or any state prescription drug assistance program. Subject to additional terms and conditions, which can be found here.

MONTHLY AND ANNUAL MAXIMUM SAVINGS: For patients with commercial drug insurance coverage for Jaypirca: You must have commercial drug insurance that covers Jaypirca and a prescription consistent with FDA-approved product labeling to pay as little as $0 for a 1-month prescription fill of Jaypirca. Month is defined as 30-days. Card savings are subject to a maximum monthly savings of wholesale acquisition cost plus usual and customary pharmacy charges and separate maximum annual savings of up to $25,000 per calendar year. Subject to Lilly USA, LLC's (“Lilly”) right to terminate, rescind, revoke, or amend Card eligibility criteria and/or Card terms and conditions which may occur at Lilly's sole discretion, without notice, and for any reason, Card expires and savings end on 12/31/2024.

You are responsible for any applicable taxes, fees and any amount that exceeds the monthly or annual maximum benefits. Savings card activation is required. This Card may be terminated, rescinded, revoked, or amended by Lilly at any time without notice and for any reason. Subject to additional terms and conditions. Eligibility criteria and terms and conditions for the Jaypirca Savings Card Program may change from time to time at Lilly's sole discretion and for any reason; the most current version can be found at Card benefits void where prohibited by law.

TRICARE® is a registered trademark of the Department of Defense (DoD), DHA.

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Filling your prescription

There are multiple ways to get Jaypirca, depending on your insurance. You may receive your medication from your hospital, your doctor, or from a specialty pharmacy.

Here's how a specialty pharmacy works with you to fill your Jaypirca prescription:

  • Your doctor sends your prescription to a specialty pharmacy
  • The specialty pharmacy will call you to schedule a date and time to deliver your Jaypirca medication (you may not recognize the phone number)
  • The specialty pharmacy can also help assess your eligibility for the Jaypirca Savings Card

This offer is invalid for patients without commercial drug insurance coverage or those whose prescription claims are eligible to be reimbursed, in whole or in part, by any governmental program. Terms and conditions apply for eligible patients.

Questions about savings? Call the Jaypirca Savings Card Support Line at 1-833-727-4589.

For all other questions regarding support, call the Lilly Oncology Support Center at 1-866-472-8663.

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Getting started on Jaypirca

Download the brochure below to see how Jaypirca works, how to take it, and some side effects you may experience with treatment.

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Support Groups

Connecting with others in your community

You are not alone on this cancer journey. There are organizations that can connect you with opportunities and support.

The Leukemia & Lymphoma Society (LLS) is the largest voluntary health organization dedicated to funding research, finding cures and ensuring access to treatments for blood cancer patients.

The Lymphoma Research Foundation (LRF) is the nation's largest nonprofit devoted to funding innovative lymphoma research and providing people with lymphoma and healthcare professionals with up-to-date information about this type of cancer.

CLL Society is the world's leading authority for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) patients devoted to serving the community through CLL education, support, advocacy and research.

This information has been provided by the listed organizations, and Lilly is not responsible for the content. Its use on this site is not intended to serve as an endorsement of the listed organizations. All third-party organization names and other trademarks are the property of their respective trademark owners. Those trademark owners are not affiliated with Lilly and they do not sponsor or endorse this material.


Warnings - Jaypirca may cause serious side effects, including:

Infections. Infections can happen during treatment with Jaypirca. These infections can be serious and may lead to death. Your doctor may prescribe vaccines and certain medicines if you have an increased risk of getting infections. Tell your doctor right away if you have fever, chills, weakness, flu-like symptoms, or any other signs of infection during treatment with Jaypirca.

Bleeding problems (hemorrhage). Bleeding problems can happen during treatment with Jaypirca. They can be serious and may lead to death. Your risk of severe bleeding may increase if you are also taking a blood thinner medicine. Tell your doctor if you have any signs or symptoms of bleeding, including:

  • blood in your stools or black stools (looks like tar)
  • pink or brown urine
  • unexpected bleeding, or bleeding that is severe or you cannot control
  • vomit blood or vomit blood that looks like coffee grinds
  • cough up blood or blood clots
  • increased bruising
  • dizziness
  • weakness
  • confusion
  • changes in your speech
  • headache that lasts a long time

Decrease in blood cell counts. Decrease in white blood cells, platelets, and red blood cells are common with Jaypirca, but can also be severe. This may increase your risk of infection, bleeding, and anemia. Your doctor should do blood tests regularly during treatment to monitor your counts.

Heart rhythm problems. Heart rhythm problems including atrial fibrillation and atrial flutter have happened in people treated with Jaypirca. Your risk for heart rhythm problems may be increased if you have high blood pressure or have had heart rhythm problems in the past. Tell your doctor if you have any of the following symptoms:

  • fast or irregular heartbeat (palpitations)
  • dizziness
  • fainting
  • chest discomfort
  • shortness of breath

Second primary cancers. New cancers have happened during treatment with Jaypirca, including cancers of the skin or other organs. Your doctor will check you for other cancers during treatment. Use sun protection when you are outside in sunlight.

Your doctor may decrease your dose, temporarily stop, or permanently stop treatment with Jaypirca if you develop severe side effects.

Common side effects

  • tiredness
  • muscle, joint, and bone pain
  • diarrhea
  • COVID-19
  • bruising
  • cough

These are not all the possible side effects with Jaypirca. Call your doctor for medical advice about side effects. You may report side effects at 1-800-FDA-1088 or

Before using

Before taking Jaypirca, tell your doctor about all your medical conditions, including if you:

  • have an infection or have been advised that you are at increased risk of infection
  • have had recent surgery or plan to have surgery. Your doctor may stop Jaypirca for a planned medical, surgical, or dental procedure
  • have bleeding problems and/or are taking blood thinner medicine
  • have or have had heart rhythm problems
  • have high blood pressure
  • have a history of other cancers, including skin cancer
  • have kidney problems
  • are pregnant or plan to become pregnant. Jaypirca can harm your unborn baby. If you are able to become pregnant, your doctor will do a pregnancy test before starting treatment
    • Females who are able to become pregnant should use effective birth control (contraception) during treatment and for at least 1 week after the last dose of Jaypirca. Tell your doctor right away if you become pregnant or think you are pregnant during treatment
  • are breastfeeding or plan to breastfeed. It is not known if Jaypirca passes into breast milk. Do not breastfeed during treatment and for at least 1 week after your final dose

Also tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking Jaypirca with certain other medicines may affect how Jaypirca or the other medicines work and can cause side effects.

How to take

  • Take Jaypirca exactly as your doctor tells you
  • Do not change your dose or stop taking Jaypirca unless your healthcare provider tells you to do so
  • Take Jaypirca tablets 1 time each day at about the same time each day
  • Take Jaypirca with or without food
  • Swallow Jaypirca tablets whole with water. Do not cut, crush, or chew the tablets
  • If you miss a dose of Jaypirca, take it as soon as you remember on the same day. If you miss taking a dose by more than 12 hours from the time you usually take Jaypirca, skip the missed dose. Take the next dose on the next day at your usual time

Learn more

Jaypirca is a prescription medicine. For more information, call 1-800-545-5979 or go to This summary provides basic information about Jaypirca but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other healthcare provider about Jaypirca and how to take it. Your doctor is the best person to help you decide if Jaypirca is right for you.


Jaypirca® is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.


Jaypirca® (JAY-PIHR-KAA) is a prescription medicine used to treat adults with:

  • mantle cell lymphoma (MCL) that has come back or did not respond to previous treatment and who have already received at least 2 treatments for their cancer, including a Bruton tyrosine kinase (BTK) inhibitor medicine.
  • chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have already received at least 2 treatments for their cancer, including a Bruton tyrosine kinase (BTK) inhibitor medicine and a B-cell lymphoma 2 (BCL-2) inhibitor medicine.

Jaypirca was approved based on how many people responded to treatment. Studies are ongoing to confirm the benefit of Jaypirca for this use.

It is not known if Jaypirca is safe and effective in children.